Estelle Marchal, PhD

Supervisor:

Dr. Alison Thompson

Program of Study:

Postdoctoral fellow

Project Title:

Synthesis of Prodigiosenes Appended with Targeting Moieties as New Chemotherapeutic Agents

Scholarships and/or Awards:

• Cancer Research Training Program (CRTP) Traineeship Award (2011-2012).
• Cancer Research Training Program Travel Award (2011)
• Winner of the 2007 outgoing mobility grants: Research fellowship-international mobility, for a research project of 5 months in Sendai (Japan). Funded by the International Doctoral College of the European University of Brittany.

Career Aspirations:

Estelle is currently working on a medicinal chemistry project in the Thompson group for the development of new drugs against breast cancer. In a near future she would like to use her skills in a pharmaceutical company for the discovery of new chemotherapeutics.

Location:

Dalhousie University

Publications:

Estelle Marchal, Philippe Uriac, Béatrice Legouin, Loïc Toupet, Pierre van de Weghe. “Cycloisomerisation of ?- and ?-acetylenic acids catalyzed by gold (I) chloride.”  Tetrahedron 2007, 63, 9979-9990.

Estelle Marchal, Jean-François Cupif, Philippe Uriac, Pierre van de Weghe. “Synthesis of 1-alkylidene-2,3-dihydro-1H-inden-2-ols through a tandem carbopalladayion / Suzuki-Miyaura sequence. ” Tetrahedron Lett. 2008, 49, 3713-3715.

Adrien Quintard, Sébastien Belot, Estelle Marchal, Alexandre Alexakis. “Aminal-pyrrolidine organocatalyst – Highly efficient and modular catalysts for ?-functionalization of carbonyl compounds.” Eur. J. Org. Chem. 2010, 927-936.

Chloée Bournaud, Estelle Marchal, Adrien Quintard, Sarah Sulzer-Mossé, Alexandre Alexakis. ‘’Organocatalyst-mediated enantioselective intramolecular Michael addition of aldehydes to vinyl sulfones.’’ Tetrahedron: Asymmetry, 2010, 21, 1666-1673.

Poigny, S.; Brunel, Y.; Marchal, E.; Uriac, P.  Methylene furanone derivatives and use of these derivatives as photoprotective agents or antioxydants.  PIERRE FABRE DERMO-COSMETIQUE, patent: 08 56441.